Aplastic Anemia

Aplastic Anemia

Aplastic Anemia INTRODUCTION:  Pancytopenia resulting from aplasia of bone marrow. Bone marrow produces very few blood cells includes red cells, white cells, and platelets (pancytopenia). Is a syndrome of chronic primary hemopoeitic failure. Classified into primary & secondary types. ETIOLOGY: Primary: Congenital Eg: Fanconi’s anemia – Autosomal recessive inheritance with defects in tolemerase activity. Idiopathic acquired […]

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Aplastic Anemia

Aplastic Anemia Q. 1 A patient aged 65 years, is diagnosed to have severe aplastic anemia. HLA compatible sibling is available. What is the BEST treatment option for this patient?  A Antithymocyte globulin followed by cyclosporine  B A conventional bone marrow transplantation from the HLA identical sibling  C A non-myeloablative bone marrow transplantation from the

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