Benzodiazipines Q. 1 Diazepam poisoning is treated by: A Flumazenil B Hemofiltration C Charcoal D Resins Q. 1 Diazepam poisoning is treated by: A Flumazenil B Hemofiltration C Charcoal D Resins Ans. A Explanation: Flumazenil REF: Harrison’s 17th ed Table e 35-4 See APPENDIX-42 for list of “Antidotes” “Specific antidote for benzodiazepine poisoning is flumazenil” Q. […]
BENZODIAZEPINE CLASSIFICATION: Long Acting Flurazepam 50-100 t1/2(hrs) Diazepam 30-60 t1/2(hrs) Nitrazepam 30 t1/2(hrs) Flunitrazepam 15-25 t1/2(hrs) Short-Acting Temazepam with t1/2 8-12 hrs Benzodiazepine without anticonvulsant property. Triazolam with t1/2 2-3 hrs Midazolam 2 t1/2(hrs) Alprazolam MOA: PHARMACOKINETICS: Short-acting BZDs: Eg: Midazolam – IV or IM as an induction agent. Rapid onset of action. Quick drug clearance. Causes anterograde amnesia, tachyphylaxis during high dose infusions. Decreased cardiovascular
