CARBAPENEM & MONOBACTUM Q. 1 A diabetic patient developed cellulitis due to S. aureus, which was found to be methicillin resistant on the antibiotic sensitivity testing. All of the following antibiotics will be appropriate except ‑ A Vancomycin B Imipenem C Teicoplanin D Linezolid Q. 1 A diabetic patient developed cellulitis due to S. aureus, […]
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CARBAPENEM & MONOBACTUM CARBAPENEM & MONOBACTUM Are beta-lactam antibiotics. Beta-lactam antibiotics – Drugs containing ß–lactam ring in their structure. Drugs: Penicillins Cephalosporins (above both discussed separately) Monobactams e.g. aztreonam Carbapenems e.g. imipenem General features: All ß-lactam antibiotics are bactericidal drugs. MOA: Bind to specific receptors (penicillin-binding proteins; PBPs) on bacterial cell membrane. Inhibits transpeptidase enzyme
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