Tag: Craniopharyngioma

Craniopharyngioma

Craniopharyngioma

Q. 1

All of the following statements regarding Craniopharyngiomas are true, except :

 A

Arise from Rathke’s pouch

 B

Can cause visual disturbances

 C

Presents with hypopituitarism in adults

 D

Usually Infrasellar in location

Q. 1

All of the following statements regarding Craniopharyngiomas are true, except :

 A

Arise from Rathke’s pouch

 B

Can cause visual disturbances

 C

Presents with hypopituitarism in adults

 D

Usually Infrasellar in location

Ans. D

Explanation:

Cranipharyngiomas are suprasellar partially calcified benign tumors that arise from remnants of Rathke’s pouch. It usually presents with headache, visual impairment, impaired growth in children and hypopituitarism in adults. Treatment modalities includes surgery, radiotherapy or both.


Reference:
Harrison’s Principles of Internal Medicine 18th edition chapter 379.


Q. 2

Commonest location for craniopharyngioma is

 A

Intrasellar

 B

Suprasellar

 C

Intraventricular

 D

Intracerebral

Q. 2

Commonest location for craniopharyngioma is

 A

Intrasellar

 B

Suprasellar

 C

Intraventricular

 D

Intracerebral

Ans. B

Explanation:

Ans. is ‘b’ i.e., Suprasellar


Q. 3

All the following are true of Craniopharyngioma except

 A

Derived from Rathke’s pouch

 B

Contains epithelial cells

 C

Present in sella or infra-sellar location

 D

Causes visual disturbances

Q. 3

All the following are true of Craniopharyngioma except

 A

Derived from Rathke’s pouch

 B

Contains epithelial cells

 C

Present in sella or infra-sellar location

 D

Causes visual disturbances

Ans. C

Explanation:

Answer is C (Present in sella or infrasellar location):

Some of these lesions arise from the sella, but most are suprasellar Q (Not infra-sellar). They arise from near the pituitary stalk and commonly extend into the supra sellar cistern.

  • Craniopharyngiomas arise from Rathke’s pouch and constitute 3-5% of all intracranial neoplasms.
  • Some of these lesions arise from the sella, but most are suprasellar Q (Not infra-sellar). They arise from near the pituitary stalk and commonly extend into the supra sellar cistern.
  • Consists of nests of cords of stratified squamous or columnar epithelium embedded in a spongy reticulum — Robbins 61h/1129
  • Visual complaints are the presenting feature in about 80% of adults and 60% of children.

Quiz In Between



Craniopharyngioma

Craniopharyngioma


CRANIOPHARYNGIOMA

  • Craniopharyngioma are benign tumours within the sella or suprasellar space.
  • They are derived from Rathke’s pouch.
  • They are large, cystic and invasive.
  • It is seen in 5- 15 years & after 65 years.
  • Contains epithelial cells.

It can be-

  1. Adamantinomatous craniopharyngioma-
  • Seen in children
  • Peripheral palisading positive
  • Keratin formation

2. Papillary craniopharyngioma-

  • Seen in adults
  • No keratin formation.

Clinical features-

  • Children with growth retardation.
  • Adults with visual disturbances.
  • Hypopituitarism and diabetes insipidus.
  • Headache, vomiting, papillaedema, hydrocephalor.

Investigations-

  • MRI

Treatment-

  • Transphenoidal surgical resection is the treatment of choice.

Exam Important

  • Craniopharyngioma are benign tumours within the sella or suprasellar space.
  • They are derived from Rathke’s pouch.
  • Contains epithelial cells.

Treatment-

  • Transphenoidal surgical resection is the treatment of choice.
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