Drug Distribution

Drug Distribution

Drug Distribution DRUG DISTRIBUTION: Mainly determined by Volume of distribution –  Volume necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma. Used as a measure for drug distribution. CALCULATION: Calculated by dividng plasma concentration attained for a particular drug administered I.V. & Initial plasma […]

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Drug Distribution

DRUG DISTRIBUTION Q. 1 Loading dose depends on:  A Volume of distribution  B Clearance  C Rate of administration  D Half life Q. 1 Loading dose depends on:  A Volume of distribution  B Clearance  C Rate of administration  D Half life Ans. A Explanation: Volume of distribution [Ref. K.D.T. 51h/e p 16, 17] After the drug

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