Excitation-Contraction Coupling

Excitation-Contraction Coupling EXCITATION-CONTRACTION COUPLING Process of muscle fiber excitation initiating its contraction – “Excitation-Contraction coupling”. COUPLING IN SKELETAL MUSCLE: Aα motor neuron – Innervates skeletal muscle fiber. Steps: Stimulated Aα motor neuron → Acton potential (AP) carried to NMJ. ↓ Acetylcholine released from pre-synaptic vesicle. ↓ Acetylcholine binds to Nm-nicotinic receptors on motor-end plate (post-synaptic membrane). ↓ Results in end-plate potential. ↓ End-plate […]