G-Protein Coupled Receptors

G-Protein Coupled Receptors G-PROTEIN COUPLED RECEPTORS INTRODUCTION: Large family of cell membrane receptors linked to effector. To enzyme/channel/carrier protein). Large heterotrimeric GTP-binding proteins (G proteins). All have seven transmembrane segments. Loops in & out of cell membrane. (I.e.7 α-helical) membrane spanning. Hormone binding site – Extracellular domain. G-protein binding site – Intracellular domain. STRUCTURE OF G-PROTEIN: G-protein […]