Suicide Psychiatric illness with highest risk of suicide are Depressive disorder Schizophrenia Alcohol dependence Other Substance dependence Borderline personality Ds Low CSF levels of 5HIAA [Hydroxy indole aceticacid ], a metabolite of serotonin associated with ↑ risk Major Risk Factors Include Male Sex Age > 45 Yrs. Divorced / Widowed Unemployed Chronic Illness Family History […]
Receptors of Integumentary System Merkel cell – Light touch receptor— Braille Slow adapting receptor Meissner’s Dermoepidermal junction Rapidly adapting 2-point discrimination Pacinian Deep dermis, rapidly adapting Pressure & vibration Ruffini’s Slowly adapting Dermal stretch & thermal receptor Free nerve endings Non myelinated, pain & temperature
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Levels of progesterone At 12 weeks-25 ng/ml At 28 weeks-80 ng/ml At term-300 ng/ml Abnormal levels of progesterone: Low levels-Ectopic pregnancy, abortion High levels-Molar pregnancy isoimmunization
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Double decidual sac sign → It consists of two concentric rings surrounding an anechoic gestational sac. The growing embryo pushes the central cavity complex and the decidua capsularis and parietalis are formed as 2 rings. The double decidual sac sign (DDSS) is a useful feature on early pregnancy ultrasound to confirm an early intrauterine pregnancy
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ChIP Chromatin Immunoprecipitation explained pictorially It aims to determine whether specific proteins are associated with specific genomic regions, such as transcription factors on promoters or other DNA binding sites, and possibly defining cistromes. ChIP also aims to determine the specific location in the genome that various histone modifications are associated with, indicating the target
Battledore placenta Battledore placenta is a placenta in which the. umbilical cord is attached at the placental margin; so. called because of the fancied resemblance to the. racquet used in badminton. The shortest distance between the cord insertion and placental edge is within 2cm. The incidence of battledore placenta is 7- 9% in singleton pregnancies,
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Selective serotonin reuptake inhibitors SSSIs are-Fluoxetine, fluvoxamine, citalopram, escitalopram, sertraline, paroxetine, vilazodone Act by blocking reuptake of serotonin First Line of T/T for Depression OCD PTSD Panic disorder GAD Phobias Side Effect – Nausea [M/C], anxiety, diarrhea, delayed ejaculation, ↓ Libido, sedation, sweating, Weight gain, delayed platelet aggregation. Serotonin Syndrome Concurrent SSRI + MAO Inhibitor,
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Structure of arginine Arginine structure explained along with image Arginine also called as Guanidinium Amino Acid with Maximum Number of Amino Group Most Basic Amino Acid Most Polar Amino Acid Test for Arginine – Saka Guchi Test
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String of beads sign CT Scans showing string of beads sign in right renal artery Seen in fibromuscular dysplasia Fibromuscular dysplasia-group of vascular lesions characterized by an idiopathic, non-inflammatory & non atherosclerotic angiopathy of small & medium sized arteries that causes abnormal growth within vessel wall.
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Pepper pot skull X-ray image of pepper pot skull Also called as salt & pepper sign Multiple tiny well defined radiolucencies seen in Hyperparathyroidism
