medicoapps

Question Homocysteine, an amino acid is present at high levels in Roshan’s blood tests as suspected by his vascular surgeon. He had presented with peripheral vascular disease. Assertion: An increase of homocysteine in serum elevates the risk of coronary artery disease Reason: Homocysteine interacts with the lysyl residue of collagen interfering with collagen cross-linking. It forms homocysteine […]

Question Essential amino acids are named so:        A. Because they are produced in the body. B. Because they are not produced in the body. C. They are not important for life. D. Every foodstuff essentially contains them.   Show Answer Correct Answer » B Explanation  Ans. ‘B’ Because they are not produced in the body. Essential

Question Scenario: Mr. Kapoor has a high level of Lipoprotein (a) and he has been warned of the high risk to his health.   Assertion: Lipoprotein (a) is very strongly associated with Myocardial infarction.   Reason: It interferes with plasminogen activation and impairs fibrinolysis. A. Both assertion and reason are true, and the reason is

Question Niacin is synthesized from: A. Phenylalanine B. Tryptophan C. Tyrosine D. Methionine   Show Answer Correct Answer » B Explanation  Ans. ‘B’ Tryptophan The liver can synthesize niacin from the essential amino acid tryptophan, but the synthesis is extremely inefficient; 60 mg of tryptophan is required to make one milligram of niacin. Tryptophan is cleaved

Question Which one of the following coenzyme is associated with glycogen phosphorylase? A. Thiamine pyrophosphate B. Tetrahydrofolate C. Flavin mononuleotide D. Pyridoxal phosphate   Show Answer Correct Answer » D Explanation Glycogen phosphorylase has a pyridoxal phosphate (PLP, derived from Vitamin B6) at each catalytic site. Pyridoxal phosphate links with basic residues and covalently forms a Schiff base. Once

Question C peptide is part of:        A. Pro-insulin B. Insulin C. ACTH D. Growth hormone   Show Answer Correct Answer » A Explanation   Ans. ‘A’ Pro-insulin The proinsulin molecule undergoes a series of site-specific peptide cleavages that result in the formation of equimolar amounts of mature insulin and C-peptide. Proinsulin has about one-third biological activity

Question All of the following amino acids are excreted in cystinuria, EXCEPT A. Cystine B. Cysteine C. Arginine D. Ornithine   Show Answer Correct Answer » B Explanation -Cystinuria is an autosomal recessive disorder caused by defective transporters in the apical brush border of proximal renal tubule and small intestinal cells. Ans:B -It is characterized

Question Hepcidin decreases iron absorption by inhibition of –  A. Hephaestin B. Ferroportin C. Divalent metal ion transporter D. Transferrin   Show Answer Correct Answer » B Explanation Ans – b). Ferroportin Iron leaves the mucosal cell via a transport protein ferroportin, but only if there is free transferrin in plasma to bind to. Once

Question Which of the lipids lacks fatty-acids? A. Glycerol B. Waxes C. Cholesterol D. Lipoprotein   Show Answer Correct Answer » C Explanation Cholesterol is present in tissues and plasma either as free cholesterol or combined with a long-chain fatty acid as cholesteryl ester, the storage form. In plasma, both forms are transported in lipoproteins.

Question What are the building blocks for most of the lipids? A. Carbohydrates B. Proteins C. Fatty acid D. None   Show Answer Correct Answer » C Explanation The building blocks of most lipids are fatty acids.  Fatty acids are aliphatic carboxylic acids and have the general formula, R—CO—OH, where COOH represents the functional group.