Image Based Question-65461

Which among the following is the most probable diagnosis for the karyotype shown below?

A. Down’s syndrome.

B. Klinefelter’s syndrome.

C. Turner syndrome.

D. None of the above.

Correct Answer » B Explanation

Ans: B. Klinefelter’s syndrome.

The karyotype shown above represents Klinefelter’s syndrome because of trisomy at sex chromosome – XXY as represented by a red box in the picture below.

Klinefelter syndrome  also known as 47,XXY or XXY, is the set of symptoms that result from two or more X chromosomes in males.

• They have 47 number of chromosomes instead of 46.
• Occurs in 1:500 to 1:1000 live male birth
• The primary feature is sterility