A 50 year old patient undergoing for splenectomy operation is advised with the following vaccination.This vaccine is prepared from ?
A. Cell surface antigen.
B. Capsular polysaccharide.
Ans:B. Capsular polysaccharide.
- Pneumococcal polysaccharide vaccine —the latest version is known as Pneumovax 23 —is the first pneumococcal vaccine derived from a capsular polysaccharide.
- PNEUMOVAX 23 is a vaccine indicated for active immunization for the prevention of pneumococcal disease caused by the 23 serotypes contained in the vaccine.
- PNEUMOVAX 23 is approved for use in persons 50 years of age or older and persons aged ≥2 years who are at increased risk for pneumococcal such as those with functional or anatomic asplenia, an immunocompromising condition (eg, HIV infection), a cerebrospinal fluid leak, a cochlear implant, or advanced kidney disease .
- Not recommended in children less than 2 years of age since polysaccharide antigens are poorly immunogenic in this age group.