Question
The most common presentation of the fetal infection derived from mother as shown in the MRI photograph is ?
A. Hepatosplenomegaly.
B. Microcephaly.
C. Cerebral calcification.
D. Chorioretinitis.
Show Answer
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Correct Answer » A
Explanation
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The fetal infection derived from mother as shown in the MRI photograph above represents congenital CMV infection.
CYTOMEGALOVIRUS(CMV)
- Also known as salivary gland virus
- CMV is the largest virus amongst herpes viruses
- They are characterized by enlargment of infected cells (cytomegalic cells) and intranuclear inclusions.
- Intranuclear inclusion is eccentrically placed and is surrounded by a halo – owl’s eye appearance
- Once infected an individual carries CMV for life
- CMV is the most common organism causing intrauterine infection.
- CMV is the most common pathogen complicating organ transplantation.
Clinical manifestations
- Most of the infections in immunocompetent persons are asymptomatic.
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