Image Based Question-69894

Identify the pathological process as shown in this histopathological examination image of Brain.

A. Coagulative Necrosis

B. Liquefactive Necrosis

C. Caseous Necrosis

D. Fat Necrosis

Correct Answer » B Explanation

Ans:B.)Liquefactive Necrosis

Image shows:Liquefactive necrosis brain. The necrosed area on right side of the field shows a cystic space containing cell debris, while the surrounding zone shows granulation tissue and gliosis.

LIQUEFACTION (COLLIQUATIVE) NECROSIS.

• Liquefaction or colliquative necrosis occurs commonly due to ischaemic injury and bacterial or fungal infections.
• It occurs due to degradation of tissue by the action of powerful  hydrolytic enzymes.
• The common examples are infarct brain and abscess cavity.
• Grossly, the affected area is soft with liquefied centre containing necrotic debris.
• Later, a cyst wall is formed.
• Microscopically, the cystic space contains necrotic cell debris and macrophages filled with phagocytosed material.
• The cyst wall is formed by proliferating capillaries, inflammatory cells, and gliosis (proliferating glial cells) in the case of brain and proliferating fibroblasts in the case of abscess cavity