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Image Based Question – 74624

Question

An elderly male patient presented with blurring of vision. Fundus examination revealed cotton wool spots on retina and systemic examination showed decreased peripheral sensations and decreased urine output.

A. Kimmelstiel-Wilson lesion

B. Crescents

C. Amyloid deposits

D. Hyaline atherosclerosis

 

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Correct Answer » A

Explanation

Answer- A. Kimmelstiel-Wilson lesion

  • Nodular Glomerulosclerosis. This is also known as inter-capillary glomerulosclerosis or Kimmelstiel-Wilson disease.
  • The glomerular lesions take theform of ovoid or spherical, often laminated, nodules of matrix situated in the periphery of the glomerulus. The nodules are PAS-positive. They lie within the mesangial core of the glomeralar lobules and can be surrounded by patent peripheral capillary loops or loops that are markedly dilated.
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