Antiphospholipid antibody syndrome
• APLA syndrome can lead to thrombosis in vessels. Depending upon which vessels get thrombosed we will get the manifestation like if cerebral vessel get thrombosed manifestation of stroke can be seen. It can even lead to thrombosis in placental blood vessels.
- Based on this size of placenta will decrease and there will be placental insufficiency.
- Abortion can happen in first trimester due to APLA but it generally causes abortion in second trimester (M/C).
- Even if there is 1 abortion due to APLA but for first trimester we need 3 abortion to say it is caused due to APLA.