AIIMS PG Exam

Question Pegloticase used in which of the following conditions? A. Chronic Gout B. Psoriatic arthritis C. RA D. Paralytic Ileus   Show Answer Correct Answer » A Explanation Ans. A. Chronic Gout * Pegloticase is a medication for the treatment of Severe Refractory Chronic Gout. * It is a third-line treatment in those in whom other treatments are […]

Question Genes involved in  X-Linked SCID-  A. EGFR B. CD23 C. IL6 D. IL2RG   Show Answer Correct Answer » D Explanation Answer-D. IL2RG * X-linked severe combined immunodeficiency (SCID) is an inherited disorder of the immune system that occurs almost exclusively in males. * Mutations in the IL2RG gene cause X-linked SCID. The IL2RG gene provides instructions for making

Question Match the following: 1. Omalizumab – 2. Itolizumab – 3. Daclizumab – 4. Belimumab – a. AntiCD6 b. ANTICd25 c. Anti IGE d. Anti IgG1 e. Anti B cell activator A. 1 – c, 2 – a, 3 – b,4 – e B. 1 – d, 2 – c, 3 – b, 4 –

Question Drugs used in urea cycle disorders to reduce ammonia? A. Phenyl butarone B. Phenyl butyrate C. L- Carnitine D. Isoleucin   Show Answer Correct Answer » B Explanation Ans: B. Phenyl butyrate  Urea cycle disorders are inherited disorders where ammonia is not turned into uric acid properly and so it builds up in the blood.   Regular intake of

Question Replacing amino acid will not change its functions A. Glutamine to Asparagine B. Aspartate and Glutamate C. Alanine to tryptophan D. None of these   Show Answer Correct Answer » A Explanation Answer- A. Glutamine to Asparagine * Glutamine and Asparagine are Amide group containing amino acids. * These belongs to same category (hydrophilic /Homophilic)

Question Which of the following is having Maximum buffering capacity A. Histidine B. Cysteine C. Tyrosine D. Arginine   Show Answer Correct Answer » A Explanation Answer-A- Histidine Maximum buffering capacity occurs at a pH equal to the pKa,  So amino acid which has pKa range near physiologic pH can act as an effective buffer

Question Which of the following statements regarding proteoglycans is true? A. consist of a core protein with GAG chains attached. B. GAG contain oxidized acid sugars C. negative charges cause to radiate out from the protein D. All of these   Show Answer Correct Answer » D Explanation Ans-D. All of these * Proteoglycans contain many

Question Z track technique is used for A. Monitoring of lithium therapy B. Monitoring of carbamazepine therapy C. Administration of long-acting depot antipsychotics D. Administration of nicotine patches   Show Answer Correct Answer » C Explanation Ans. C. Administration of long-acting depot antipsychotics * Z-Tracking technique- Stretch/displace the skin by pulling it laterally away from the

Question Assertion: In a patient admitted to hospital for community acquired pneumonia, combination therapy of beta lactams and azithromycin is given. Reason : This combination covers gram positive organisms and anaerobes. A. Both reason and assertion are true B. Assertion is true but reason is false. C. Assertion is true but reason is partially true

Question Prucalopride drug is ? A. 5HT4 agonist B. 5HT2b agonist C. 5HT2b antagonist D. 5HT2a agonist   Show Answer Correct Answer » A Explanation Ans. A. 5HT4 agonist * Prucalopride is a drug acting as a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalizing bowel movements. * Approved