PGI Chandigarh

Question Proteus mirabilis is inherently resistant to? A. Ampicillin B. Colistin C. Doxycycline D. Nitrofurantoin E. Cefalosporins   Show Answer Correct Answer » B:C:D Explanation Ans. B, C & D A High level of resistance (>60% of isolates) has been observed for cefuroxime, tetracycline, Polymyxin B, Colistin Sulfute & Nitrofutantoin. P. mirabilis remains susceptible to […]

Question Alkylating agents include all except? A. Gemcitabin B. Busulfan C. Azathioprine D. Cyclophosphamide E. Cisplatin   Show Answer Correct Answer » A:C Explanation Ans. A & C Gemcitabin is pyrimidine antagonist & azathipurine is a purine antagonist. They both come under the category of antimetabolites. Other three are alkylating agents.

Question True regarding paracetamol intoxication in children? A. Large single dose of 5mg/kg is hepatotoxic B. Acetylcysteine is specific antidote C. Serum enzymes are raised to 1000 iu/1 D. Bilirubin can be raised within 24 hours E. Acetylcysteine administration is beneficial even after 24 hours   Show Answer Correct Answer » B:C:D:E Explanation Ans. B,

Question A 14 year old boy presented with hereditary spherocytosis. Which of the following indices is/are increased? A. LDH B. MCHC C. MCV D. Urine urobilinogen  E. Haptoglobin   Show Answer Correct Answer » A:B:D Explanation Ans. A, B & D Spherocytosis + peripheral smear shows microspherocytes which are small RBCs without central pallor (Normally

Question Superior vena cava syndrome is commonly seen in? A. Lymphoma B. Multiple myeloma C. Small cell carcionoma lung D. Squamous cell carcinoma lung E. Squamous cell carcinoma lung   Show Answer Correct Answer » A:C:D Explanation Ans. A, C & D Superior vena cava syndrome (SVCS) is a group of symptoms caused by obstruction

Question Correct combination of dye and the structure they stain is/are? A. Sudan III – fat B. Oil red 0 – calcium C. Oil red 0 – calcium D. PAS – collagen E. Hematoxylin – DNA   Show Answer Correct Answer » A:C:E Explanation Ans. A, C & E OiI red O, Sudan black and

Question Which of the following is not stored at cold temperature? A. Whole blood B. Packed RBCs C. Leucoreduced RBCs D. Platelet concentrate  E. Fresh frozen plasma   Show Answer Correct Answer » D Explanation Ans. D At present, the most widely used protocol for the storage of red blood cells (packed RBCs. washed, leukodepleted,

Question Which of the following is/are anti apoptotic factor ? A. Bax B. BCL-X C. Bcl-2 D. Bax  E. Mcl-1   Show Answer Correct Answer » B:C:E Explanation Ans. B, C & E Genes/proteins regulating apoptosis Certain proteins/genes are involved in regulation of apoptosis. They either facilitate (proapoptotic) or inhibit (antiapoptotic) apoptosis.

Question True statement regarding proto-oncogene is/are? A. Responsible for normal cell proliferation B. Need some stimuli to get activated C. Oncoproteins produced by oncogenes are nonspecific D. Point mutation activates RAS E. p53 is an important protooncogene   Show Answer Correct Answer » A:B:D Explanation Ans. A, B & D Protoncogenes are required for normal

Question Microcytic Hypochromic anemia is seen in? A. Sideroblastic anemia B. Lead poisoning C. Anemia of chronic disease D. Anemia of renal disease E. Vit B12 deficiency   Show Answer Correct Answer » A:B:C Explanation Ans. A, B & C Sideroblastic anemia, Lead poisoning & Anemia of chronic disease are characterized by microcytic hypochronic anemia.