PGI Chandigarh

Question True regarding acute graft rejection is? A. T-cell mediated B. Preformed anti-HLA antibodies mediated C. Strong predictor for chronic renal transplant rejection D. Can be reversed by increasing the dose of immunosuppressives E. Poor graft survival   Show Answer Correct Answer » A:B:C:D:E Explanation Ans. A, B, C, D & E Acute cellular rejection […]

Question Cytokines induced rise in body temperature is seen in? A. Viral fever B. Heat stroke C. Thyroid storm D. Malignant neurolept syndrome E. Lymphoma   Show Answer Correct Answer » A:E Explanation Ans. A & E Viral fever is due to cytokine induced rise in temperature. Hyperthermia also has no agreed definition; it has

Question Regulatory T-cells? A. Prevent autoimmune diseases B. Activate other T & B cells C. Suppress tumor immunity D. Associated with CD25, CD4 & FOX P3 E. Associated with CD33, CD 117 & FOX L3   Show Answer Correct Answer » A:C:D Explanation A, C & D Regulatory T-cells maintain tolerance to self-antigen, and prevent

Question True regarding Down syndrome is? A. Short neck B. Short nose C. Extra large ear D. Large fissured tongue E. Underdeveloped ear ossicles   Show Answer Correct Answer » A:D Explanation Ans. A & D Down syndrome is characterized by Short neck with excess skin at the back of the neck ln Down syndrome

Question True regarding Down syndrome is/are? A. Associated with intellectual impairment B. Abnormality in 21st chromosome C. Maternal age > 35 is a risk factor D. Paternal age > 35 is a risk factor E. Most common type is translocation type   Show Answer Correct Answer » A:B:C Explanation Ans. A, B & C Cognitive/intellectual

Question WHO grade -1 meningioma is/are? A. Hemangioblastoma B. Fibrous meningioma C. Clear cell meningioma D. Rhabdoid meningioma E. Transitional cell meningioma   Show Answer Correct Answer » A:B:E Explanation Ans. A, B & E Hemangioblastoma, Fibrous meningioma & Transitional cell meningioma are WHO grade I Meningioblastomas. Clear cell meningioma is grade 2 & Rhabdoid

Question Secondary amyloidosis is seen in? A. Lung abscess/empyma B. Pulmonary tuberculosis C. Bronchiectasis D. Idiopathic pulmonary fibrosis E. Primary pulmonary hypertension   Show Answer Correct Answer » A:B:C Explanation Ans. A, B & C SAA is produced in liver as an acute phase reactant in inflammatory Process, The SAA is released into the circulation

Question True regarding pulmonary alveolar proteinosis is/are? A. Antibodies to GM-CSF B. Deposition of PAS positive material in lung alveoli C. Hemorrhagic material deposition in bronchioalveolar lavage D. Milky material deposition in bronchioalveolar lavage E. More common in elderly   Show Answer Correct Answer » A:B:D Explanation Ans. A, B & D In adults, the

Question True regarding hemophilia is/are? A. Hemophilia A constitutes 80-85% B. Platelet count is decreased in Hemophilia B C. Cryoprecipitate can be given in hemophilia B D. In severe hemophilia A factor 8 is less than 5% E. Each unit of factor VIII /kg increases circulating factor VIII by 2%   Show Answer Correct Answer

Question True regarding cystic fibrosis is/are? A. Renal failure B. Autosomal dominant C. Mutation in CFTR gene D. Azoospermia and infertility E. Sweat CI- and Na+ concentration increased   Show Answer Correct Answer » C:D:E Explanation Ans. C, D & E Renal involvement & failure is not a feature of cystic fibrosis. Cystic fibrosis is