Lipoprotein Structure
LIPOPROTEINS
- Free fatty acids (FAA) is metabolically most active of the plasma lipids.
- Lipids are transported in the form of lipoproteins.
- Non polar lipid contains cholesterol ester, cholesterol, phospholipid, triacylglycerol.
- Protein part of lipoprotein is apolipoprotein.
Major lipoproteins according to density are-
- Chylomicrons- These are principal form in which dietary lipids (exogenous lipids) are carried from intestine to liver.
- Very low density lipoproteins (VLDL)
- Low density lipoproteins (LDL)- major source of cholesterol to peripheral tissues.
- Intermediate density lipoproteins (IDL)
- High density lipoproteins (HDL)
Separation of Lipoproteins-
- Electrophoresis-
- Chylomicrons have no mobility and remains at orginial position
- HDL has maximum mobility and move longest distance.
2. Ultracentrifugation-
- Chylomicrons are largest with maximum lipid contents.
Exam Important
- Free fatty acids (FAA) is metabolically most active of the plasma lipids.
- Non polar lipid contains cholesterol ester, cholesterol, phospholipid, triacylglycerol.
- Protein part of lipoprotein is apolipoprotein.
- Chylomicrons- These are principal form in which dietary lipids (exogenous lipids) are carried from intestine to liver.
- Low density lipoproteins (LDL)- major source of cholesterol to peripheral tissues.
Electrophoresis-
- Chylomicrons have no mobility and remains at orginial position
- HDL has maximum mobility and move longest distance.
Ultracentrifugation-
- Chylomicrons are largest with maximum lipid contents.
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