Mycobacteria other than Tuberculosis-MOTTS/Atypical mycobacteria
Mycobacteria other than Tuberculosis-MOTTS/Atypical mycobacteria
Runyon Classification of Mycobacteria:
TB complex
- M tuberculosis
- M africanum
- M bovis
Photochromogens
- M asiaticum
- M kansasii
- M marinum
- M simiae
Scotochromogens
- M flavescens
- M gordonae
- M scrofulaceum
- M szulgai
Nonchromogens
- M avium complex
- M celatum
- M haemophilum
- M gastri
- M genavense
- M malmoense
- M nonchromogenicum
- M shimoidei
- M terrae
- M trivale
- M ulcerans
- M xenopi
Rapid growers
- M abscessus
- M fortuitum group
- M chelonae group
- M phlei
- M smegmatis
- M vaccae
Diseases
Mycobacterium marinum/M.balanei
- Aquarium granuloma/ Fishtank granuloma/swimming pool granuloma
- The person usually has a history of exposure to swimming pools, salt water aquarium, or ocean fish.
- The lesions appear as reddish bumps (papules) that slowly grow into purplish nodules.
- A skin biopsy and culture is usually needed to confirm the diagnosis. A PPD tuberculin skin test will usually be positive.
M. chelonae, M.fortuitum M.abscessus
- Rapidly growing atypical mycobacteria causing lung infections
Saprophytic mycobacteria not associated with human illness.
- M. phlei
- M. smegmatis
- M. gordona
- M. paratuberculosis
M. Kansasii
- Produce pulmonary and systemic disease indistinguishable from tuberculosis
Mycobacterium bovis
- Equally pathogenic to M tuberculosis for humans.
Mycobacterium ulcerans
- Causative organism for Buruli ulcer disease.
- Third most frequent mycobacterial pathogen, after M. tuberculosis and M. leprae.
- Children are most often affected
- Infected individuals develop severe ulceration involving the skin and subcutaneous tissue that is often progressive unless treated effectively.
- Surgical excision and grafting are usually needed. Antimicrobial treatment is often unsuccessful
Exam Important
Runyon Classification of Mycobacteria:
TB complex
- M tuberculosis
- M africanum
- M bovis
Photochromogens
- M asiaticum
- M kansasii
- M marinum
- M simiae
Scotochromogens
- M flavescens
- M gordonae
- M scrofulaceum
- M szulgai
Nonchromogens
- M avium complex
- M celatum
- M haemophilum
- M gastri
- M genavense
- M malmoense
- M nonchromogenicum
- M shimoidei
- M terrae
- M trivale
- M ulcerans
- M xenopi
Rapid growers
- M abscessus
- M fortuitum group
- M chelonae group
- M phlei
- M smegmatis
- M vaccae
Diseases
Mycobacterium marinum/M.balanei
- Aquarium granuloma/ Fishtank granuloma/swimming pool granuloma
M. chelonae, M.fortuitum M.abscessus
- Rapidly growing atypical mycobacteria causing lung infections
Saprophytic mycobacteria not associated with human illness.
- M. phlei
- M. smegmatis
- M. gordona
- M. paratuberculosis
M. Kansasii
- Produce pulmonary and systemic disease indistinguishable from tuberculosis
Mycobacterium bovis
- Equally pathogenic to M tuberculosis for humans.
Mycobacterium ulcerans
- Causative organism for Buruli ulcer disease.
Don’t Forget to Solve all the previous Year Question asked on Mycobacteria other than Tuberculosis-MOTTS/Atypical mycobacteria
