Phospholipids

PHOSPHOLIPIDS

• Phospholipid= Fatty acid+ Glycerol+Phosphoric acid+ nitrogenous base
• Function is transduction of signals in cell membrane.

2 types-

1. Glycerophospholipids
2. Sphingophospholipids

1. Glycerophospholipids (phosphoglycerides)- that contains glycerol as alcohol. They are-

a) Phosphatidylcholine (lecithin)

• Most abundant phospholipids in cell membrane.
• Dipalmitoyl lecithin in lungs
• Insufficient production of Dipalmitoyl lecithin- acute pulmonary distress syndrome in premature infants.

b) Phosphatidylethanolamine (Cephalin)- contains ethanolamine.

c) Plasmogens- platelet activating factor

d) Cardiolipin (Diphosphatidylglycerol) – is a major lipid of inner mitochondrial membrane.

• It has antigenic properties (only humans).
• Deficiency causes- Barth syndrome.

Don’t Forget to Solve all the previous Year Question asked on PHOSPHOLIPIDS