Phospholipids

PHOSPHOLIPIDS


PHOSPHOLIPIDS

  • Phospholipid= Fatty acid+ Glycerol+Phosphoric acid+ nitrogenous base
  • Function is transduction of signals in cell membrane.

2 types-

  1. Glycerophospholipids
  2. Sphingophospholipids

1. Glycerophospholipids (phosphoglycerides)- that contains glycerol as alcohol. They are-

a) Phosphatidylcholine (lecithin)

  • Most abundant phospholipids in cell membrane.
  • Dipalmitoyl lecithin in lungs
  • Insufficient production of Dipalmitoyl lecithin- acute pulmonary distress syndrome in premature infants.

b) Phosphatidylethanolamine (Cephalin)- contains ethanolamine.

c) Plasmogens- platelet activating factor

d) Cardiolipin (Diphosphatidylglycerol) – is a major lipid of inner mitochondrial membrane.

  • It has antigenic properties (only humans).
  • Deficiency causes- Barth syndrome.

Exam Important

1.Glycerophospholipids (phosphoglycerides)- that contains glycerol as alcohol. They are-

a) Phosphatidylcholine (lecithin)

  • Most abundant phospholipids in cell membrane.
  • Dipalmitoyl lecithin in lungs
  • Insufficient production of Dipalmitoyl lecithin- acute pulmonary distress syndrome in premature infants.

 b) Phosphatidylethanolamine (Cephalin)- contains ethanolamine.

c) Plasmogens- platelet activating factor

d) Cardiolipin (Diphosphatidylglycerol) – is a major lipid of inner mitochondrial membrane.

  • It has antigenic properties (only humans).
  • Deficiency causes- Barth syndrome.
Don’t Forget to Solve all the previous Year Question asked on PHOSPHOLIPIDS

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