Phopholipids
| A | Phosphatidylethanolamine | |
| B | Cardiolipin | |
| C | Phosphatidylcholine | |
| D | Sphingomyelin |
| A | Phosphatidylethanolamine | |
| B | Cardiolipin | |
| C | Phosphatidylcholine | |
| D | Sphingomyelin |
Sphingomyelin = phosphorylcholine + ceramide
Ceramide = fatty acid + sphingosine
Sphingosine = condensing palmitic acid with a decarboxylated serine and then reducing the product
Glycerol never is involved in the structure of sphingomyelin. Phosphatidylethanolamine, cardiolipin, phosphatidylcholine, and phosphatidylinositol are synthesized using phosphatidic acid as the basic building block Phosphatic acid is diacylglycerol with a phosphate ester on carbon three; therefore, glycerol is the backbone of all of these compounds. FAQ Sphingomyelin :-
– Membranous myelin sheath that surrounds nerve cell axons.
– It is the only sphingolipid NOT derived from Glycerol.
– Associated with increased accumulation in Niemann-Pick Disease.
Function of phospholipid in cell membrance is:
| A |
Cell to cell variation |
|
| B |
Transduction of Signals |
|
| C |
Transmembrane preparation of protein |
|
| D |
DNA replication |
Function of phospholipid in cell membrance is:
| A |
Cell to cell variation |
|
| B |
Transduction of Signals |
|
| C |
Transmembrane preparation of protein |
|
| D |
DNA replication |
B i.e. Transduction of signals
Which of the following phospholipid has antigenic acitivity ‑
| A |
Plasmalogen |
|
| B |
Cardiolipin |
|
| C |
Phosphatidylcholine |
|
| D |
Sphingomyelin |
Which of the following phospholipid has antigenic acitivity ‑
| A |
Plasmalogen |
|
| B |
Cardiolipin |
|
| C |
Phosphatidylcholine |
|
| D |
Sphingomyelin |
Ans. is ‘b i.e., Cardiolipin
- Cardiolipin is the only human glycerophospholipid that possess antigenic properties”
- Cardiolipin is the major lipid of inner mitochondrial membrane.
Which of the following is not a phospholipid ‑
| A |
Lecithine |
|
| B |
Plasmalogen |
|
| C |
Cardiolipin |
|
| D |
Ganglioside |
Which of the following is not a phospholipid ‑
| A |
Lecithine |
|
| B |
Plasmalogen |
|
| C |
Cardiolipin |
|
| D |
Ganglioside |
Ans. is ‘d’ i.e., Ganglioside
Phospholipids are :
- Glycerophospholipids (glycerol containing) :- Phosphatidylcholine (lecithin), phosphatidylethanolamine (cephaline), phosphatidylserine, phosphatidylinositol, plasmalogens, lysophospholipids, cardiolipin.
- Sphingophospholipids (sphingosine containing) :- Sphingomyeline




