Thyroid Storm

Thyroid Storm


THYROID STORM

  • Thyroid storm or thyrotoxic crisis is rare and is a life threatening exacerbation of hyperthyroidism.

 ETIOLOGY

  • Acute illness (stroke, infection, trauma, diabetic ketoacidosis)
  • Surgery
  • Inadequate control of hyperthyroidism
  • Radioactive treatment of hyperthyroidism

 CLINICAL FEATURES-

  • Fever, delirium, coma
  • Vomiting diarrhea and jaundice
  • Cardiac failure, arrhythmia or hyperthermia

 TREATMENT-

  • Propylthiouracil (drug of choice)
  • Stable iodide blocks thyroid hormone synthesis via Wolff- Chaikoff effect.
  • Potassium iodide
  • Porpranolol
  • Glucocorticoids
  • Calcium channel blocker

Exam Important

  • Thyroid storm or thyrotoxic crisis is rare and is a life threatening exacerbation of hyperthyroidism.

ETIOLOGY

  • Acute illness (stroke, infection, trauma, diabetic ketoacidosis)
  • Surgery
  • Inadequate control of hyperthyroidism
  • Radioactive treatment of hyperthyroidism

TREATMENT-

  • Propylthiouracil (drug of choice)
  • Stable iodide blocks thyroid hormone synthesis via Wolff- Chaikoff effect.
  • Potassium iodide
  • Porpranolol
  • Glucocorticoids
  • Calcium channel blocker
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