Vitamin B3 Deficiency
Uses-
- As lipid modifying drug
- Reduces triglyceride and LDL-C levels
Vitamin B3 Deficiency-
Pellagra-
- Caused due to niacin deficiency
- Common in people consuming maize and sorghum (poor in niacin & tryptophan and rich in leucine)
Clinical Manifestations-
Characterized by 4Ds-
Dermatitis, Diarrhea, Dementia and Death
- Casal’s necklace– rash form around neck
- Apathy
- Depressive psychosis
- Hartnup disease
- Carcinoid syndrome

Vitamin B3 Toxcity-
- Cutaneous flushing
- Gastric irritation
- Hepatic toxicity
- Macular edema and cysts
- Hyperuricemia
- Glucose intolerance
Exam Important
Pellagra-
- Caused due to niacin deficiency
- Common in people consuming maize and sorghum (poor in niacin & tryptophan and rich in leucine)
Clinical Manifestations-
Characterized by 4Ds-
- Dermatitis, Diarrhea, Dementia and Death
- Casal’s necklace– rash form around neck
Don’t Forget to Solve all the previous Year Question asked on Vitamin B3 Deficiency



