Vitamin B3 Deficiency

Vitamin B3 Deficiency


Uses-

  • As lipid modifying drug
  • Reduces triglyceride and LDL-C levels

Vitamin B3 Deficiency-

Pellagra-

  • Caused due to niacin deficiency
  • Common in people consuming maize and sorghum (poor in niacin & tryptophan and rich in leucine)

Clinical Manifestations-

Characterized by 4Ds-

            Dermatitis, Diarrhea, Dementia and Death

  • Casal’s necklace– rash form around neck
  • Apathy
  • Depressive psychosis
  • Hartnup disease
  • Carcinoid syndrome

Vitamin B3 Toxcity-

  • Cutaneous flushing
  • Gastric irritation
  • Hepatic toxicity
  • Macular edema and cysts
  • Hyperuricemia
  • Glucose intolerance

Exam Important

Pellagra-

  • Caused due to niacin deficiency
  • Common in people consuming maize and sorghum (poor in niacin & tryptophan and rich in leucine)

Clinical Manifestations-

Characterized by 4Ds-

  • Dermatitis, Diarrhea, Dementia and Death
  •  Casal’s necklace– rash form around neck
Don’t Forget to Solve all the previous Year Question asked on Vitamin B3 Deficiency

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