Candida

Candida

Q. 1

True about Candida albicans is –

 A

Candida is pathogenic to mice

 B

It’s growth is inhibited by Griseofulvin

 C

Candida shows mycelia and chlamydospores on corn meal agar

 D

All

Q. 1

True about Candida albicans is –

 A

Candida is pathogenic to mice

 B

It’s growth is inhibited by Griseofulvin

 C

Candida shows mycelia and chlamydospores on corn meal agar

 D

All

Ans. C

Explanation:

Ans. is ‘c’ i.e., Candida shows mycelia and chlamy dospores on corn meal agar

Candida

.   Candida albicans is the most common cause of mucosal candidiasis.

.  All candida species pathogenic for humans are also encountered as commensals of humans, particularly in the mouth, stool and vagina.

.  They grow rapidly on simple media as oval budding cells at 25° to 37°C.

.  In tissue, both yeasts and pseudohyphae are present.

.  Candida albicans is differentiated by other candida :

– It forms true hyphae (mycelia) or germ tubes when grown in serum.

– It forms thick walled large spores called chlamydospores when grown in corn meal agar.

– It is dimorphic.

Remember -4 Candida albicans can produce yeast, true hyphae and pseudohyphae.


Q. 2

The following is not true of candida albicans ‑

 A

Yeast like fungus

 B

Forms chlamydospores

 C

Blastomeres seen in isolates

 D

Causes meningitis in immunocompromised

Q. 2

The following is not true of candida albicans ‑

 A

Yeast like fungus

 B

Forms chlamydospores

 C

Blastomeres seen in isolates

 D

Causes meningitis in immunocompromised

Ans. C

Explanation:

Ans. is ‘c’ i.e., Blastomeres seen in isolates

  • Candida is a yeast like fungus.
  • Forms thick walled chlamydospores when grown on cornmeal agar.
  • Systemic infections such as septicemia, endocarditis and meningitis may occur as terminal complications in persons on prolonged immunosuppression.

Q. 3

Candidiasis is associated with all except-

 A

OCP user

 B

IUCD user

 C

Diabetes

 D

Pregnancy

Q. 3

Candidiasis is associated with all except-

 A

OCP user

 B

IUCD user

 C

Diabetes

 D

Pregnancy

Ans. B

Explanation:

Ans. is ‘b’ i.e., IUCD user


Q. 4

Normal commensal of skin are

 A

Staphylococcus aureus

 B

Candida

 C

Propioni bacterium acnes

 D

b and c both

Q. 4

Normal commensal of skin are

 A

Staphylococcus aureus

 B

Candida

 C

Propioni bacterium acnes

 D

b and c both

Ans. D

Explanation:

B, C i.e. Candida; Propioni bacterium acnes

Resident flora (normal commensal) of skin consists of permanently present mixture of several non pathogenic microorganisms. It includes :

Coagulase negative Staphylococcus epidermidis (not coagulase positive staphylococcus aureus)Q and peptococcus.

Diptheroid bacilli which may be aerobic (eg Corynebacterium minutissimum) or anerobic (eg propionibacterium acnes)Q.

Brevibacterium, a hemolytic streptococcus (S.viridians), enterococci (S. fecalis), gram –ye Coliform bacilli & acme tobacter’ (Harellea) and acid fast non pathogenic mycobacterium (in areas rich in sebaceous secretion eg external ear & genitalia).

Fungus such as candida and yeast eg Malassezia.


Q. 5

Which is a yeast like fungi:        

September 2007

 A

Cryptococcus

 B

Candida

 C

Blastomyces

 D

Histoplasma

Q. 5

Which is a yeast like fungi:        

September 2007

 A

Cryptococcus

 B

Candida

 C

Blastomyces

 D

Histoplasma

Ans. B

Explanation:

Ans. B: Candida

Yeast like fungi grow partly as yeast and partly as elongated cells resembling hyphae.The latter form a pseudomycelium. Candida albicans is a pathogenic yeast-like fungus.


Q. 6

All are true about candida except ‑

 A

Pseudohyphae seen

 B

Produce chlamydospore

 C

It is a mould

 D

It is a dimorphic fungus

Q. 6

All are true about candida except ‑

 A

Pseudohyphae seen

 B

Produce chlamydospore

 C

It is a mould

 D

It is a dimorphic fungus

Ans. C

Explanation:

Ans. is ‘c’ i.e., It is a mould

Candida

  • Candida is a yeast like fungus (not mould).
  • Candida albicans is the most common cause of mucosal candidiasis.
  • All candida species pathogenic for humans are also encountered as commensals of humans, particularly in the mouth, stool and vagina.
  • They grow rapidly on simple media as oval budding cells at 25° to 37°C.
  • In tissue, both yeasts and pseudohyphae are present.
  • Candida albicans is differentiated by other candida :
  • It forms true hyphae (mycelia) or germ tubes when grown in serum.
  • It forms thick walled large spores called chlamydospores when grown in corn meal agar.
  • It is dimorphic.

Remember → Candida albicans can produce yeast, true hyphae and pseudohyphae.

  • A rapid method of identifying C. albicans is based on its ability to form germ tubes within two hours when incubated in human serum at 37°C Reynolds – Braude phenomenon ( Also known as germ tube test)

Q. 7

The image is shown of a dimorphic fungus, inhabiting 80% of intestinal tract, colon, and mouth and which is the most common cause of fungal infections worldwide.One of its species shows positive Germ Tube test.Identify this fungus .

 A

Coccidiomycosis.

 B

Penicillium.

 C

Candida.

 D

Aspergillus.

Q. 7

The image is shown of a dimorphic fungus, inhabiting 80% of intestinal tract, colon, and mouth and which is the most common cause of fungal infections worldwide.One of its species shows positive Germ Tube test.Identify this fungus .

 A

Coccidiomycosis.

 B

Penicillium.

 C

Candida.

 D

Aspergillus.

Ans. C

Explanation:

Ans:C.)Candida

The fungus shown in the photograph above represents candida.

Candida

  • It is a genus of yeasts and is the most common cause of fungal infections worldwide.
  • Candida albicans is the most commonly isolated species.
    • C. albicans is a diploid fungus populating the human body worldwide, inhabiting 80% of everyone’s intestinal tract, colon, and mouth with no problems.
    • It is normally commensal of humans but can be pathogenic if a person’s immunity is lowered or there is a change in natural flora or physiology.
  • Morphology:
  • It is dimorphic.
    • C. albicans can take on either a unicellular (yeast) or multicellular (hyphae, pseudohyphae) form.
  • In Gram stained smears, Candida appears as gram positive budding yeast cells (blastoconidia) and/or pseudohyphae showing regular points of constriction.Spores form on the pseudohyphae called chlamydospores
  • Culture:
    • Candida appears as large, round, white or cream colonies, which emit a yeasty odor on agar plates at room temperature.
  • Germ tube positive:A rapid method of identifying C. albicans is based on its ability to form germ tubes within two hours when incubated in human serum at 37°C Reynolds – Braude phenomenon ( Also known as germ tube test)

Q. 8

Most common oral infection in diabetes mellitus

 A

Candida

 B

Aspergillus

 C

Streptococcus

 D

Stphylococcus

Q. 8

Most common oral infection in diabetes mellitus

 A

Candida

 B

Aspergillus

 C

Streptococcus

 D

Stphylococcus

Ans. A

Explanation:

Ans. is ‘a’ i.e., Candida

  • Individuals with DM have a greater frequency and severity of infection. The reasons for this include incompletely defined abnormalities in cell-mediated immunity and phagocyte function associated with hyperglycemia, as well as diminished vascularization. Hyperglycemia aids the colonization and growth of a variety of organisms (candida and other fungal species).


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