Carcinoma of prostate
| A |
Peripheral |
|
| B |
Centre |
|
| C |
Verumontum |
|
| D |
None of the above |
Which is the most common site of carcinoma prostate?
| A |
Peripheral |
|
| B |
Centre |
|
| C |
Verumontum |
|
| D |
None of the above |
85% of prostate carcinoma arise from the peripheral zone.
Ninety five percent of tumors are adenocarcinoma.
Prostate carcinoma rarely occur before the age of 40 years, and the incidence increases with age.
- PSA is elevated in 60% of men with prostate cancer. Levels above 4ng/ml is considered abnormal.
- Levels of PSA can be elevated with age and BPH.
- Falsely elevated PSA can be seen following cystoscopy, prostate biopsy, or urethral catheterization.
- PSA is not elevated following digital rectal examination.
Ref: CURRENT Diagnosis & Treatment: Surgery, 13e, chapter 38
Trans rectal ultrasonogram in evaluation of carcinoma prostate most useful for:
| A |
Taking guided biopsy |
|
| B |
Identifying seminal vesicle invasion |
|
| C |
Nodal sampling |
|
| D |
Measuring the extent of invasion |
Trans rectal ultrasonogram in evaluation of carcinoma prostate most useful for:
| A |
Taking guided biopsy |
|
| B |
Identifying seminal vesicle invasion |
|
| C |
Nodal sampling |
|
| D |
Measuring the extent of invasion |
Ans. is ‘a’ Taking guided biopsy
“TRUS is the imaging technique most frequently used to assess the primary tumor, but its chief use is directing prostate biopsies, not staging” – Harrison
- Thus primary role of TRUS is guiding prostate biopsies
- Other uses are
– assessing extent of invasion if cancer is detected.
– measurement of prostate volume which is needed in the calculation of the PSA density. – also used in performance of cryosurgery & brachytherapy.
Which is not used in carcinoma prostate ‑
| A |
Estrogen |
|
| B |
Progesterone |
|
| C |
Cyproterone acetate |
|
| D |
Flutamide |
Which is not used in carcinoma prostate ‑
| A |
Estrogen |
|
| B |
Progesterone |
|
| C |
Cyproterone acetate |
|
| D |
Flutamide |
Ans. is ‘c’ i.e., Conservative treatment
In carcinoma prostate with matastasis which is raised
| A |
ESR |
|
| B |
Alkaline phosphatase |
|
| C |
Acid phosphatase |
|
| D |
All |
In carcinoma prostate with matastasis which is raised
| A |
ESR |
|
| B |
Alkaline phosphatase |
|
| C |
Acid phosphatase |
|
| D |
All |
Ans. is ‘b’ i.e., Alkaline phosphatase
70 year old man with Ca.prostate with osteoblastic secondaries in pelvis and lumbar vertebra showed well differentiated Adeno Carcinoma prostate on needle biopsy. He is idealy treated by –
| A |
Radical prostectomy |
|
| B |
TURP |
|
| C |
Radiation |
|
| D |
Hormonal manipulation |
70 year old man with Ca.prostate with osteoblastic secondaries in pelvis and lumbar vertebra showed well differentiated Adeno Carcinoma prostate on needle biopsy. He is idealy treated by –
| A |
Radical prostectomy |
|
| B |
TURP |
|
| C |
Radiation |
|
| D |
Hormonal manipulation |
Ans. is ‘d’ i.e., Hormonal manipulation
