HALLUCINOGENS
Flash backs are seen with
| A |
LSD |
|
| B |
Cocaine |
|
| C |
Opiate |
|
| D |
Amphetamine |
Flash backs are seen with
| A |
LSD |
|
| B |
Cocaine |
|
| C |
Opiate |
|
| D |
Amphetamine |
A i.e. LSD
- Spontaneous recurrence of LSDQ, or sometimes cannabis use experience even during a withdrawl state is known as Flash back
- LSD intoxication causes bad tripsQ ie acute panic reaction in which the individual experiences a loss of control over his self.
A 16-year-old boy suffering from drug abuse presents with cross-over of sensory perceptions, such that, sounds can be seen and colors can be heard. Which of the following is the most likely agents responsible for drug abuse:
| A |
Cocaine |
|
| B |
LSD |
|
| C |
Marijuana |
|
| D |
PCP |
A 16-year-old boy suffering from drug abuse presents with cross-over of sensory perceptions, such that, sounds can be seen and colors can be heard. Which of the following is the most likely agents responsible for drug abuse:
| A |
Cocaine |
|
| B |
LSD |
|
| C |
Marijuana |
|
| D |
PCP |
B i.e. (LSD)
– Lysergic acid diethylamide (LSD) has potent psychedelic & hallucinogenic effects and produce a variety of bizarre and offer conflicting perceptual and mood changes, including visual illusions, synesthesias (reflex hllucination = sensory modalities cross over) extreme lability of moodQ. and sometimes bad trip (panic episode). It also produces tachycardia, hypertension, pupillary dilation, tremor, and hyperpyrexia. Phencyclidine (PCP) or angel dust, a NMDA receptor blocker, is widely used in veterinary medicine to briefly immobilize large animals (dissociative anesthesia). It produces agitation, excitement, impaired motor coordination, dysarthria and analgesia at low doses; whereas signs of intoxication include horizontal or vertical nystagmus, flushing, diaphoresis, and hyperacusis; higher doses (5-10 mg) produce profuse salivation , vomiting, myoclonus, fever, stupur, coma, convulsions, opisthotonus and decerebrate posturing. Behavioral changes include distortion of body image, disorganization of thinking, and feeling of estrangementQ
– Flunitrazepam (Rohypnol), a benzodiazepine used for insomnia has strong hypotic, anxiolytic and amnesia producing effects. It is also k/a date – rape drug or roofies and overdose can be treated with flumazenil. GHB (Gamma hydroxy butyric acid = Xyrem) is FDA approved treatment for narcopepsy with abuse potential producing euphoria & disinhibition. GABAB antagonists can reverse its sedating effects and opioid antagonists (naloxone, naltrexone) can attenuate GHB effects on dopamine release.
All of the following are hallucinogens, except –
| A |
LSD |
|
| B |
Phenylcyclidine |
|
| C |
Mescaline |
|
| D |
Methylphenidate |
All of the following are hallucinogens, except –
| A |
LSD |
|
| B |
Phenylcyclidine |
|
| C |
Mescaline |
|
| D |
Methylphenidate |
Ans. is ‘d’ i.e., Methylphenidate
Drug that does not cause dependence:
UPSC 14
| A |
LSD |
|
| B |
Cannabis |
|
| C |
Benzodiazepine |
|
| D |
Opioids |
Drug that does not cause dependence:
UPSC 14
| A |
LSD |
|
| B |
Cannabis |
|
| C |
Benzodiazepine |
|
| D |
Opioids |
Ans. LSD
A young city dweller presented with history of drug abuse and complaining of change in perception, like hearing sights and seeing sounds. Substance responsible for this:
AI 12
| A |
LSD |
|
| B |
Phencyclidine |
|
| C |
Cocaine |
|
| D |
Amphetamine |
A young city dweller presented with history of drug abuse and complaining of change in perception, like hearing sights and seeing sounds. Substance responsible for this:
AI 12
| A |
LSD |
|
| B |
Phencyclidine |
|
| C |
Cocaine |
|
| D |
Amphetamine |
Ans. LSD
treatment of withdrawal is required in ‑
| A |
LSD |
|
| B |
Opium |
|
| C |
Alcohol |
|
| D |
Amphetamine |
treatment of withdrawal is required in ‑
| A |
LSD |
|
| B |
Opium |
|
| C |
Alcohol |
|
| D |
Amphetamine |
Ans. is ‘a’ i.e., LSD
Clinically significant withdrawal syndrome (requires treatment) :-Alcohol, opioids, amphetamines, Barbiturates, BZDs, Nicotine.
No or minimal clinically significant withdrawal syndrome (requires no treatment) :- LSD (nil), Cannabis (minimal).
Drug with no dependance or addiction ‑
| A |
Morphine |
|
| B |
Amphetamines |
|
| C |
Benzodiazipines |
|
| D |
LSD |
Drug with no dependance or addiction ‑
| A |
Morphine |
|
| B |
Amphetamines |
|
| C |
Benzodiazipines |
|
| D |
LSD |
Ans. is ‘d’ i.e., LSD
[R4 Niraj Ahuja &/e p. 37)
