Lathyrism
An agricultural labourer presented with progressive spastic paralysis is diagnosed of having neurolathyrism. It results from consumption of:
| A |
Aflatoxin |
|
| B |
BOAA |
|
| C |
Pyruvic acid |
|
| D |
Sanguinarine |
An agricultural labourer presented with progressive spastic paralysis is diagnosed of having neurolathyrism. It results from consumption of:
| A |
Aflatoxin |
|
| B |
BOAA |
|
| C |
Pyruvic acid |
|
| D |
Sanguinarine |
BOAA is –
| A |
Beta-oxalyl amino alanine |
|
| B |
Beta-oxalo acetoacetate |
|
| C |
Beta-oxalyl aminoacetate |
|
| D |
Beta-oxalyl acetylacetate |
BOAA is –
| A |
Beta-oxalyl amino alanine |
|
| B |
Beta-oxalo acetoacetate |
|
| C |
Beta-oxalyl aminoacetate |
|
| D |
Beta-oxalyl acetylacetate |
Ans. is ‘a’ i.e., Beta-oxyalyi amino alanine
BOAA stands for Beta-oxalyl-amino alanine.
o BOAA causes Lathyrism.
Lathyrism
- Lathyrism is a paralysing disease of humans and animals.
In humans it affects nervous system —r Neurolathyrism.
- In animals it affects skeletal system —, Osteolathyrism (odoratisnt).
Neurolathyrism
Disease affects young men between 15-45 years.
- It is characterized by spastic paralysis of lower limbs.
interventions for prevention and control
- Vitamin C prophylaxis
3 Banning the crop
o Removal of toxin: Steeping method and Parboiling o Education
o Genetic approach
o Socio-economic changes
Lathyrism results due to –
| A |
Aflatoxin |
|
| B |
BOAA |
|
| C |
Pyruvic acid |
|
| D |
Sanguinarine |
Lathyrism results due to –
| A |
Aflatoxin |
|
| B |
BOAA |
|
| C |
Pyruvic acid |
|
| D |
Sanguinarine |
Ans. is ‘b’ i.e., BOAA
- Lathyri ST11 is caused by lathyrus sativus, commonly known as “Khesari dhal”.
o The toxin present in lathyrus seeds has been identified as Beta oxalyl aminoulanine (BOAA).
True about lathyrism:
PGI 09
| A |
Caused by Aspergillus flavus |
|
| B |
Prevented by parboiling |
|
| C |
Sanguinarine is the toxic principle |
|
| D |
All |
True about lathyrism:
PGI 09
| A |
Caused by Aspergillus flavus |
|
| B |
Prevented by parboiling |
|
| C |
Sanguinarine is the toxic principle |
|
| D |
All |
Ans. Patient develops spastic paraplegia
Neurolathyrism is due to ‑
| A |
Argemone oil |
|
| B |
Jhunjhunia |
|
| C |
Khesari dal |
|
| D |
None |
Neurolathyrism is due to ‑
| A |
Argemone oil |
|
| B |
Jhunjhunia |
|
| C |
Khesari dal |
|
| D |
None |
Ans. is ‘c’ i.e., Khesari dal
