Gastritis Q. 1 Which of the following conditions would most likely be associated with chronic gastritis (Type A) resulting from autoimmune destruction of parietal cells? A Decreased growth of luminal bacteria B Decreased likelihood of developing gastric carcinoma C Decreased plasma concentration of gastrin D Increased production of macrocytic red blood cells Q. 1 Which […]
Gastritis GASTRITIS Gastritis is inflammation of the gastric mucosa. Gastritis may be of 2 types- Acute Chronic 1. Acute gastritis- It is a transient acute inflammatory involvement of the stomach, mainly mucosa. Etiology- Diet & personal habits- alcohol, smoking, malnutrition. Infections- bacterial (H. Pylori), viral infections Drugs- NSAIDs, aspirin, cortisone Severe stress, trauma, surgery Classification- Acute
Gastritis GASTRITIS Autoimmune (Type A) gastritis H. pylori (Type B) gastritis (90%) Associations – Autoimmune disease; thyroiditis, diabetes mellitus, Graves disease Antrum not affected Antibodies to parietal cells components (H+,K+-ATPase, or proton pump, intrinsic factor) à Hypochlorhydria à G cell hyperplasia à hypergastrinemia Intrinsic factor deficiency à pernicious anemia Microadenoma of enterochromaffin like (ECL) à gastric adenocarcinoma, carcinoid Reduced serum pepsinogen I concentration Histology
Gastritis Q. 1 Which of the following conditions would mostly likely be associated with chronic gastritis (Type A) resulting from autoimmune destruction of parietal cells? A Decreased growth of luminal bacteria B Decreased likelihood of developing gastric carcinoma C Decreased plasma concentration of gastrin D Increased production of macrocytic red blood cells Q. 1 Which
