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Process Of Synaptic Inhibition

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Process Of Synaptic Inhibition PROCESS OF SYNAPTIC INHIBITION Transmission at synapses can be inhibited by naturally existing mechanism. Types of inhibition: Post-synaptic/Direct inhibition. Pre-synaptic/Indirect inhibition. Renshaw cell/Feedback inhibition. Feed-forward inhibition. POST-SYNAPTIC/DIRECT INHIBITION: Result of “Decreased post-synaptic neuron excitability consequent to previous post-synaptic neuron discharge”. Inhibition due to inhibitory neurotransmitter release. GABA/glycine. Due to post-synaptic membrane hyperpolarization (IPSP). Typically seen in stretch reflex Specifically called “Reciprocal inhibition”. Due to inhibitory […]

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Skeletal Muscle Physiology – Structure & Types Of Muscle Fibers

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Skeletal Muscle Physiology – Structure & Types Of Muscle Fibers SKELETAL MUSCLE PHYSIOLOGY – STRUCTURE & TYPES OF MUSCLE FIBERS Skeletal muscle constitutes nearly 40% of total body mass COMPONENTS OF SKELETAL MUSCLE: Made up of numerous muscle fibers/muscle cells. “Sarcolemma”: Cell membrane surrounding each muscle cell/fiber. Contains thousands of myofibrils. Myofibril consists of series interlocking actin & myosin myofilaments. TYPES

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Skeletal Muscle Physiology – Structure & Types Of Muscle Fibers

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SKELETAL MUSCLE PHYSIOLOGY – STRUCTURE & TYPES OF MUSCLE FIBERS Q. 1 Receptor responsible for malignant hyperthermia is?  A Nicotinic receptor  B Ryanodine receptor  C Muscarinic receptor   D None Q. 1 Receptor responsible for malignant hyperthermia is?  A Nicotinic receptor  B Ryanodine receptor  C Muscarinic receptor   D None Ans. B Explanation:   Ryanodine receptor REF:

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Skeletal Muscle Contraction & Relaxation -Mechanism

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Skeletal Muscle Contraction & Relaxation -Mechanism SKELETAL MUSCLE CONTRACTION & RELAXATION -MECHANISM CONTRACTION PROCESS: Muscle contraction/shortening occurs due to sliding of filaments (actin on myosin). Basic contractile unit of muscle – Sarcomere. TYPES OF MUSCLE PROTEINS: Four types involved: Actin, Myosin, Tropomyosin, & Troponin. 1. Myosin: Protein with thick filaments. Myosin type in skeletal muscle – Myosin-II.

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Features Of Sensory Receptors

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Features Of Sensory Receptors FEATURES OF SENSORY RECEPTORS Features include,  Generator potential (Receptor potential). Adaptation. Coding of intensity of stimulus (Intensity discrimination). Sensory unit & receptor field. Law of projection (Sensory projection). Muller’s law of specific nerve energies. Proprioceptive sensations. 1. GENERATOR POTENTIAL: Also referred as “Receptor potential”. Steps: On adequate stimulus application —> Receptor

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Skeletal Muscle Contraction & Relaxation -Mechanism

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SKELETAL MUSCLE CONTRACTION & RELAXATION -MECHANISM Q. 1 Intermediate filaments (IFs) help link adjacent sarcomeres together in skeletal muscle. Which of the following proteins is an intermediate protein used diagnostically in pathologic cases to indicate muscle origin?  A Actin       B Desmin  C Actinin  D Clathrin Q. 1 Intermediate filaments (IFs) help link adjacent sarcomeres together

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Inverse Stretch Reflex

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Inverse Stretch Reflex INVERSE STRETCH/GOLGI TENDON/NEGATIVE STRETCH REFLEX Bi-synaptic reflex. Initiated by Golgi tendon organ located in muscle tendon. GOLGI TENDON ORGAN: Consists of net-like/ramified collection of knobby nerve endings among tendon fascicles. About 3-25 muscle fiber per golgi tendon organ. Types of Golgi tendon organs: Two types –  High threshold. Low threshold. 1. High threshold type: Respond to passive muscle stretching.

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