Parkinsonism
Parkinsonism ETIOPATHOGENESIS: The degeneration of neurons in- Substantia nigra pars compacta Nigrostriatal tract This results in deficiency of dopamine in striatum which controls muscle tone and coordinates movements. Tyrosine Hydroxylase enzymes is believed to be deficient in Parkinsonism Nerve fibers from cerebral cortex and thalamus secrete acetylcholine in the neostriatum causing excitatory effects that initiate and […]
