A 22 year old female presented with complain of pain and local swelling in the wrist joint.
X ray shows the following features.What can be the most probable diagnosis?
A. Giant cell tumor
C. Ewing’s Sarcoma
D. Osteoid Osteoma
Ans:A. Giant Cell Tumor.
In the image,X-ray shows a giant cell tumor in the lower end of the radius bone in the wrist.Soap bubble Appearance is seen
Giant cell tumor of the bone
- It is a relatively uncommon tumor that is characterized by the presence of multinucleated giant cells.
- It is slightly more common in females, has a predilection for the epiphyseal/metaphyseal region of long bones, and generally occurs in the third to fourth decade.
- Although classified as a benign tumor, it has been observed to metastesize to the lungs in up to 5% of cases
- Most giant cell tumors occur in the long bones ,and almost all are located at the articular end of the bone.
- Common sites include the proximal tibia, distal femur, distal radius, and proximal humerus.Giant cell tumors may also occur in the vertebra.
- Patients often complain of pain and swelling at the affected site. Pathologic fracture is present in 10% of patients.
- On X-ray, giant-cell tumors (GCTs) are lytic/lucent and expansile lesions,without sclerotic margins and usually without a periosteal reaction. that have an epiphyseal location and grow to the articular surface of the involved bone.They may show characteristic ‘soap bubble’ appearance.
- Surgery is the treatment of choice if the tumor is determined to be resectable. Curettage is a commonly used technique.