Image Based Question – 71996

A. Mitochondrial inheritance

B. Y linked inheritance

C. X linked recessive inheritance

D. Autosomal recessive inheritance

Correct Answer » A Explanation

Ans:A. Mitochondrial inheritance.

MITOCHONDRIAL INHERITANCE

• There is a 100% chance of all offspring developing the phenotype by inheriting the gene from an affected female parent.

• Only females will transmit the phenotype (ie, there is no male transmission of the disease).

• Males and females are equally affected by the disease.

ORGAN-BASED MITOCHONDRIAL DISEASES

• Leber hereditary optic neuropathy

• Mitochondrial myopathies (MERRF, MELAS)