Question
The following microscopic appearance is that of schwannoma—a nerve sheath tumor most commonly involving the cerebellopontine angle. What does the area marked with arrow represent?
A. Myxoid tissue
B. Antony A pattern
C. Schwannoma Antoni type B
D. Antony C pattern Verocay body
Show Answer
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Correct Answer » C
Explanation
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Ans: C. schwannoma Antoni type B
(Ref Robbins 9/e p257. 854, 8/e p1340).
- Area marked with arrow represents growth pattern.
- Here tumor is less densely cellular & consists of loose meshwork of cells, microcysts and myxoid stroma, Antoni B pattern of growth.
Schwannoma – Histopathology:
- Verocay bodies- “Nuclear-free zones” of processes lie between regions of nuclear palisading.
In Antoni Agrowth pattern:
- Elongated cells with cytoplasmic processes are arranged in fascicles in areas of moderate to high cellularity and scant stromal matrix.
In Antoni B growth pattern:
- Tumor less densely cellular & consists of a loose meshwork of cells, microcysts and myxoid stroma.
