Hyperphosphatemia
A patient has hyperphosphatemia with short metacarpals and associated cataract. The diagnosis is:
| A |
Pseudohypoparathyroidism |
|
| B |
Hypophophatasia |
|
| C |
Hyperparathyroidism |
|
| D |
Osteomalacia |
A patient has hyperphosphatemia with short metacarpals and associated cataract. The diagnosis is:
| A |
Pseudohypoparathyroidism |
|
| B |
Hypophophatasia |
|
| C |
Hyperparathyroidism |
|
| D |
Osteomalacia |
Answer is A (Pseudohypoparathyroidism):
The presence of hyperphosphatemia (Serum phosphate) along with characteristic brachydactyly suggests the diagnosis of pseudohypoparathyroidism.
Pseudohypoparathyroidism
- This is a hereditary disorder associated with symptoms and signs of hypoparathyroidism despite an elevated PTH level (pseudohypoparathyroidism)
- This is produced as a result of deficient end organ response to PTH.
Hypocalcemia with hyperphosphatemia are seen in:
| A |
CRF |
|
| B |
Pseudohypoparathyroidism |
|
| C |
Vit. D deficiency |
|
| D |
a and b |
Hypocalcemia with hyperphosphatemia are seen in:
| A |
CRF |
|
| B |
Pseudohypoparathyroidism |
|
| C |
Vit. D deficiency |
|
| D |
a and b |
Answer is A and B (CRF and Pseudohypoparathyroidism):
CRF and Pseadohypoparathyroidism are associated with Hypocalcemia and Hyperphosphatemia
Hypocalcemia with Hyperphosphatemia:
- Chronic Renal Failure
- True Hypoparathyroidism
- Pseudo hypoparathyroidism
- Tumor lysis syndrome
- Rhabdomyolysis
