ENZYME INHIBTION Q. 1 The presence of a noncompetitive inhibitor can be implicated in which of the outcome? A Leads to both an increase in the Vmax of a reaction and an increase in the Km B Leads to a decrease in the observed Vmax C Leads to a decrease in Km and Vmax D […]
ENZYME INHIBITION ENZYME INHIBITION Enzyme inhibitor binds with enzyme and decreases a catalytic activity. Types of Enzyme Inhibition- Reversible Irreversible Allosteric Reversible Inhibition– binds through non-covalent bonds and activity of enzyme is restored. Divided into- a) Competitive inhibitor– Km increased, Vmax unchanged. E.g.- Succinate dehydrogenase by melanate. b) Non competitive inhibitor- Km unchanged, Vmax decrease,
