Growth Hormone
Growth Hormone GROWTH HORMONE (GH)/SOMATOTROPIN Polypeptide. Synthesized & secreted by somatotropes. Subtype of acidophilic cells in adenohypophysis. PHYSIOLOGICAL EFFECTS: Two major action – Stimulation of skeletal growth. Regulation of metabolism. 1. STIMULATION OF SKELETAL GROWTH: Mediated by “Somatomedins”/“Insulin-like Growth Factors” (IGF). Synthesized in liver. Somatomedin (IGF-1) stimulates proliferation of chondrocytes & osteocytes. Increases chondroitin sulfate deposition in cartilage. Increases […]


