NEET PG

Gout- Purine metabolism disorder

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Gout- Purine metabolism disorder  GOUT Gout is a metabolic disease associated with overproduction of uric acid. (Hyperuricemia) Two types of Gout- Primary Gout– defect in enzymes leads to overproduction of purine nucleotides. Enzymes are- Deficiency of HGPRTase Increased activity PRPP synthetase Increased activity of PRPP amindotransferase Glucose 6- phosphatase deficiency 2. Secondary Gout-  Increased production of uric […]

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Gout- Purine metabolism disorder

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Gout- Purine metabolism disorder Q. 1 Acute Gouty arthritis is seen early in treatment following  A Probenecid  B Allopurinol  C Colchicine  D Rasburicase Q. 1 Acute Gouty arthritis is seen early in treatment following  A Probenecid  B Allopurinol  C Colchicine  D Rasburicase Ans. B Explanation: Allopurinol REF: Goodman Gillman manual of pharmacology and therapeutics 2008 edition

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Role Of Usg In Obstetrics

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Role Of Usg In Obstetrics INDICATIONS: Indication of First Trimester Ultrasonography : Intrauterine pregnancy Suspected ectopic pregnancy Vaginal bleeding (in all trimesters) Fetal anomalies (anencephaly 10 weeks) Suspected molar pregnancy Gestational age Multiple pregnancy (chorionicity) To confirm cardiac activity(6weeks) Screening of aneuploidy Evaluation of pelvic/adnexal masses (all trimesters) Indication of Second and Third Trimester USG Gestational

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Humam Development Index

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Humam Development Index Humam Development Index The Human Development Index (HDI) is published annually by the UNDP The Human Development Index (HDI) is a composite statistic used to rank countries by level of “human development” and separate developed (high development), developing (middle development), and underdeveloped (low development) countries. HDI is a composite index combining indicators representing three

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Aflatoxicosis

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Aflatoxicosis Aflatoxicosis Aflatoxins are produced primarily by filamentous fungi Aspergillus flavus and Aspergillus parasiticus. Types Four types of aflatoxins have been described B1(most potent liver carcinogen) B2 G1 G2 Animals consuming feeds contaminated with aflatoxin B1 leads to secretion in the milk of aflatoxin M1 and M2 Effects of aflatoxins When consumed in large doses, they are lethal

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Aflatoxicosis

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Aflatoxicosis Q. 1 You are investigating the exposure to aflatoxin in a young man with hepatocellular carcinoma. There is a history of consumption of soya sauce which could have been contaminated. Which is the likely organism responsible?  A Fusarium  B Rhizopus  C Candida  D Aspergillus Q. 1 You are investigating the exposure to aflatoxin in

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Endemic ascites

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Endemic ascites Endemic ascites Endemic ascites is caused by a hepatotoxin – pyrrolizidine alkaloid found in weed seeds of Crotolaria (Jhunjhunia). Epidemiology Kusmi block of Sarguja district of Madhya Pradesh during the years 1973 and 1976 There was an outbreak among the tribals.  Mortality rate was 40%. How Millet seeds gets contaminated: Investigation by the National Institute of Nutrition

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