NEET PG

Antimetabolites

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Antimetabolites ANTIMETABOLITES USED IN CANCER CHEMOTHERAPY Compounds with structural similarity to precursors of purines or pyrimidines (Synthetic Nucleotides), or compounds that interfere with purine or pyrimidine synthesis are called antimetabolites.  Compound Use Nucleoside analogue Bromodeoxyuridinea Study cell proliferation Thymidine analogue Allopurinal Anti gout drug Hypoxanthine analogue Azathiopine Immunosuppressant Purine analogue Mycophenolic Acid-Potent Reversible uncompetitive inhibitor […]

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Antimetabolites

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Antimetabolites Q. 1 Antimetabolite drug used for the treatment of gout?  A Allopurinol  B Zidovudine  C Azathioprine  D None of the above Q. 1 Antimetabolite drug used for the treatment of gout?  A Allopurinol  B Zidovudine  C Azathioprine  D None of the above Ans. A Explanation: Synthetic nucleotide used in the treatment of Gout-Alloourinol. Q.

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Maternal Pelvis

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Maternal Pelvis Q. 1 Most important diameter of pelvis during labour is :  A Interspinous diameter of outlet  B Oblique diameter of inlet  C AP diameter of outlet  D Intertubercular diameter Q. 1 Most important diameter of pelvis during labour is :  A Interspinous diameter of outlet  B Oblique diameter of inlet  C AP diameter

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Metabolism of Pyrimidine

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Metabolism of Pyrimidine METABOLISM OF PYRIMIDINE  Biosynthesis of Pyrimidine- Its main site is liver. It takes place in cytoplasm and mitochondria organelle. Pyrimidine nucleotides are- Cytidine monophosphate (CMP) Uridine monophosphate (UMP) Thymidine monophosphate (TMP)  Precursors for de novo synthesis of pyrimidine are. Glutamins provides N3 Aspartic acid furnishes C4, C5, C6, and N1 CO2 provides C2  De Novo

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Physiological Changes During Pregnancy

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Physiological Changes During Pregnancy GENITAL ORGANS: The body of the uterus- Hyperplasia Height increases (7.5 cm to 35cm) Weight increases (50g to 1000g ) Uterine ligaments →hypertrophy Dextrarotated uterus→tilted and twisted to the right (80%) Lower uterine segment :Formed from isthmus (4th month to 10 cm ) Cervix  Edema and congestion, and becomes soft  Mucus

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Physiological Changes During Pregnancy

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Physiological Changes During Pregnancy Q. 1 Which of the following is seen during pregnancy?  A Respiratory alkalosis  B Respiratory acidosis  C Metabolic alkalosis  D Metabolic acidosis Q. 1 Which of the following is seen during pregnancy?  A Respiratory alkalosis  B Respiratory acidosis  C Metabolic alkalosis  D Metabolic acidosis Ans. A Explanation: Respiratory alkalosis REF: Dutta

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Fetal Skull

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Fetal Skull AREAS OF SKULL: Vertex : Quadrangular area bounded anteriorly by the bregma and coronal sutures behind by the lambda and lambdoid sutures and laterally by lines passing through the parietaleminences. Brow : Bounded on one side by the anterior fontanel and coronal sutures and on  other side by root of the nose and

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Fetal Skull

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Fetal Skull Q. 1 Which is the longest diameter of fetal skull?  A Occipito frontal  B Suboccipitobregmatic  C Biparietal  D Bitemporal Q. 1 Which is the longest diameter of fetal skull?  A Occipito frontal  B Suboccipitobregmatic  C Biparietal  D Bitemporal Ans. A Explanation: Maximum diameter of foetal head is Occipitofrontal (11.50cm) that is the engaging

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