Anti-Neutrophil Cytoplasmic Antibody (Anca) Q. 1 Which of the following types of hepatitis is associated with an immune-mediated vasculitis characterized by p-ANCA antibodies? A Hepatitis A B Hepatitis B C Hepatitis C D Hepatitis D Q. 1 Which of the following types of hepatitis is associated with an immune-mediated vasculitis characterized by p-ANCA antibodies? A […]
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ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY (ANCA) ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES(ANCA) ANCA’s are the heterogeneous group of autoantibodies directed against antigens which are found within primary granules of neutrophil and in the lysosomes of monocytes and in endothelial cells. Description based on immunofluorescence pattern of staining of ethanol-fixed neutrophils. With immunofluorescence two principal patterns are recognized: 1. Anti-proteinase-3 (PR3-ANCA) Previously referred to as “Cytoplasmic
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LANGERHANS CELL HISTIOCYTOSIS (LCH) Q. 1 Langerhans cell histiocytosis true is all except ‑ A Peak incidence less than 3 years of age B Radiosensitive C Diffuse form is known as litter-sewe-disease D Gonadal involvement occurs Q. 1 Langerhans cell histiocytosis true is all except ‑ A Peak incidence less than 3 years of age
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LANGERHANS CELL HISTIOCYTOSIS (LCH) LANGERHANS CELL HISTIOCYTOSIS. Previously referred to as “Histiocytosis X”. Before identifying “unknown X”; X refers to Langerhans, Langerhans cells are dendritic cells functioning as antigen presenting cells, present mostly in skin – epidermis. Unusual proliferation of immature dendritic cells called “Langerhans cell histiocytosis”. Considered neoplastic with oncogenetic mutations of BRAF. Pathological morphology: Proliferating Langerhans cells
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TUMOR PROTEIN 53 (TP53) Q. 1 About p53 all are true except A Encodes 53k Da protein B Located on Chr. 17 C Arrests cell cycle at GI phase D Wild type p53 is associated with childhood tumors. Q. 1 About p53 all are true except A Encodes 53k Da protein B Located on Chr.
MEDICAL TERMINATION OF PREGNANCY (MTP) ACT Q. 1 For MTP consent is taken from A Wife only B Husband only C Both D Neither Q. 1 For MTP consent is taken from A Wife only B Husband only C Both D Neither Ans. A Explanation: A i.e. Wife only – MTP Act 1971 allows registered
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MEDICAL TERMINATION OF PREGNANCY (MTP) ACT MEDICAL TERMINATION OF PREGNANCY (MTP) ACT The MTP act was introduced in 1971 Consent of husband is not required. Abortion cannot be performed on request of husband, if women herself is not willing. Under MTP Act, pregnancy cannot be terminated after 20 weeks of pregnancy. Above 20 weeks, the
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Undertaker Fracture,Stalking,para-suicide, heat and cold stroke Q. 1 Which among the following sites are involved in “undertakers fracture”? A Skull B Cervical spine C Pelvis D Mandible Q. 1 Which among the following sites are involved in “undertakers fracture”? A Skull B Cervical spine C Pelvis D Mandible Ans. B Explanation: The so called undertaker
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Undertaker Fracture,Stalking,para-suicide, heat and cold stoke Introduction: Undertaker’s fracture is an artifact related to poor handling of the corpse characterized by subluxation of the lower cervical spine from tearing of the intervertebral disc at C6-C7 vertebral level. It occurs due to sudden fall of the head over occipital region. stalking – physical or electronic via phone
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Ethylene glycol & Boric acid poisoning Q. 1 Which of the properties accounts for ethanol’s use in ethylene glycol poisoning? A Competitive inhibitor of NADPH oxidase B Competitive inhibitor of alcohol dehydrogenase C Competitive inhibitor of aldehyde dehydrogenase D Non-competitive inhibitor of aldehyde dehydrogenase Q. 1 Which of the properties accounts for ethanol’s use in
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